Spontaneous involution of optic pathway lesions in neurofibromatosis type 1: serial contrast MR evaluation.

Autor:	Parazzini C; Department of Neuroradiology, Scientific Institute H.S. Raffaele, University of Milan, Italy., Triulzi F, Bianchini E, Agnetti V, Conti M, Zanolini C, Maninetti MM, Rossi LN, Scotti G
Jazyk:	angličtina
Zdroj:	AJNR. American journal of neuroradiology [AJNR Am J Neuroradiol] 1995 Sep; Vol. 16 (8), pp. 1711-8.
Abstrakt:	Purpose: To evaluate with contrast MR the evolution in size, signal, and contrast enhancement of optic pathway lesions in four patients with neurofibromatosis type 1. Methods: The four reported patients are children with ages ranging from 21 months to 13 years affected by neurofibromatosis type 1 and optic pathway lesions. No treatment of the optic pathway lesions was carried out in these patients. They have been followed by serial contrast MR. Results: In all patients a change in size, signal, and enhancement of optic pathways lesions was noted with time, and in the last follow-up study a marked reduction in size and enhancement of optic pathway lesions was observed in all cases. Conclusions: Modification and regression of optic pathway lesions with spontaneous disappearance of the enhancement is demonstrated. This finding could have a crucial influence on the therapeutic approach of the optic pathway lesions.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu