Familial glioblastoma.
| Autor: | Arruda WO; Unidade de Ciências Neurológicas, Hospital das Nações, Curitiba, Brasil., Clemente RS, Ramina R, Pedrozo AA, Pilotto RF, Pinto Júnior W, Bleggi-Torres LF |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 1995 Jun; Vol. 53 (2), pp. 312-7. |
| DOI: | 10.1590/s0004-282x1995000200025 |
| Abstrakt: | The authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities. Cytogenetic study of the tumor cells disclosed several abnormalities: 46, XX, 7q-/46, XX, -2, 4p-, 7p-, +15/46, XX. Some aspects about genetics of glial neoplasms are discussed. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|