| Autor: |
Scudds RA; Faculty of Applied Health Sciences, University of Western Ontario, London, Ontario N6G 1H1 Canada Faculty of Medicine, University of Western Ontario, London, Ontario N6G 1H1 Canada Southeast Arthritis Care Centre, Charlotte, NC 28204 USA Peel Memorial Hospital, Brampton, Ontario L6W 2Z8 Canada Parkwood Hospital, London, Ontario N6C 5J1 Canada., Janzen V, Delaney G, Heck C, McCain GA, Russell AL, Teasell RW, Varkey G, Woodbury GM |
| Jazyk: |
angličtina |
| Zdroj: |
Pain [Pain] 1995 Jul; Vol. 62 (1), pp. 69-77. |
| DOI: |
10.1016/0304-3959(94)00232-4 |
| Abstrakt: |
To assess the efficacy of 4% topical lidocaine in spheno-palatine blocks, a randomized controlled trial was carried out on patients with chronic muscle pain syndromes. Sixty-one patients (42 with fibromyalgia (FM) and 19 with myofascial pain syndrome (MPS)) completed the trial. Outcome measures included pain intensity, a daily pain diary, headache frequency, sensitivity to pressure using a dolorimeter, anxiety, depression, and sleep quality. Patients were randomized to receive either 4% lidocaine or sterile water (placebo) 6 times over a 3-week period. Both subjects and investigators were blind to treatment allocation. The results showed that 4% lidocaine had no superiority over placebo in any of the outcome measures. Twenty-one subjects (35%) showed a decrease in pain which was greater than 30% of their baseline value. Of these 21 subjects, 10 received lidocaine and 11 received placebo. These data suggest that, in this population, 4% lidocaine is no better than placebo in the treatment of chronic muscle pain. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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