Mitogenic and protective activity associated with a lipopolysaccharide from Coxiella burnetii.

Autor: Paquet A Jr, Rael ED, Klassen D, Martinez I, Baca OG
Jazyk: angličtina
Zdroj: Canadian journal of microbiology [Can J Microbiol] 1978 Dec; Vol. 24 (12), pp. 1616-8.
DOI: 10.1139/m78-259
Abstrakt: A purified lipopolysaccharide (LPS) isolated from the rickettsial agent of Q fever, Coxiella burnetii phase 1, possesses some of the in vivo and in vitro biological properties previously only associated with bacterial endotoxins. The Coxiella LPS is mitogenic for guinea pig leukocytes, induces non-specific resistance in mice to virulent Candida albicans, causes dermal Schwartzman reactions, and is positive by the limulus lysate assay.
Databáze: MEDLINE