| Autor: |
Bogomolova NN, Boriskin IuS, Bektemirova MS, Ianova NN, Matevosian KSh |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy virusologii [Vopr Virusol] 1980 May-Jun (3), pp. 315-8. |
| Abstrakt: |
Properties of rabies virus (RV) persisting in chronically infected cultures (CIC): HEp-2--RV and BHK-RV were studied. RV from the HEp-2-RV system retained its pathogenicity for mice for more than 3 years of observation. RV from the BHK-RV system lost this property after 50 passages in CIC. Both RV variants from CIC formed plaques in CER cells, showed marked immunogenic activity in mice, had no interferon-inducing activity in BHK-21 cells, and were not temperature-sensitive. Electron microscopic examinations of CIC culture fluids showed virions of bullet-like, oval, or spherical shapes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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