| Autor: |
Abdel-Aleem AM, Abdel-Kader MA, El-Koussi AA |
| Jazyk: |
angličtina |
| Zdroj: |
Die Pharmazie [Pharmazie] 1980; Vol. 35 (7), pp. 394-8. |
| Abstrakt: |
Some new amides of substituted oxamic acid which embody different moieties of the anti-inflammatory drugs were prepared through two routes of synthesis. The physico-chemical properties as well as the anti-inflammatory activity of these compounds were determined. Preliminary pharmacological testing revealed the superiority of most of the screened compounds as anti-inflammatory agents with relatively low toxicity as compared with acetylsalicylic acid. Correlation between structure and biological activity was suggested. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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