| Autor: |
Paponov VD, Gromov PS, Rupasov VV |
| Jazyk: |
ruština |
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1980 Aug; Vol. 90 (8), pp. 163-5. |
| Abstrakt: |
The dissociation of histones H1, H2B and H2A from DNA was shown for the first time in the medium of physiological ionic strength (0.15M NaCl + 0.7 mM Na-phosphate buffer, pH 7.0) by treating the whole histone--DNA complex with high concentrations of whole histone from calf thymus chromatin. The histones can be separated into three groups according to the strength of their binding to DNA: H1 < H2B + H2A < H3 + H4. It is suggested that histone octamer is not a conservative formation and the histone content of nucleosomes may change under physiological conditions being affected by competition of chromatin components for DNA. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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