Contamination of human melanoma cell lines by mouse L cells.

Autor: Muir PD, Gunz FW
Jazyk: angličtina
Zdroj: Pathology [Pathology] 1977 Oct; Vol. 9 (4), pp. 301-9.
DOI: 10.3109/00313027709094450
Abstrakt: Five of 8 cell lines from human melanomas originally established elsewhere were found to consist exclusively of mouse cells when examined in our laboratory some months after their receipt. Cytogenetic studies, including G- and C-banding, showed that the mouse cells in all cultures had originated from a single cell line, identified as the L-line. Contamination probably occurred, one year before its discovery, in a laboratory where L cells and human melanoma cells were briefly kept in the same incubator.
Databáze: MEDLINE