Identification of a macromolecular inhibitor of in vitro lymphocyte proliferation in human seminal plasma as bound spermine.

Autor: Curry MC, Hussain JI, Smith CJ, Allen JC
Jazyk: angličtina
Zdroj: European journal of cell biology [Eur J Cell Biol] 1980 Jun; Vol. 21 (2), pp. 180-2.
Abstrakt: The excluded fraction from Sephadex G-25 separation of human seminal plasma has been found to suppress lymphocyte transformation and DNA synthesis [7]. We have shown that most of its in vitro activity is due to contamination by spermine which binds tenaciously to, and co-elutes with the protein.
Databáze: MEDLINE