A virilizing hilus-cell tumour in an African patient with Turner's syndrome.

Autor: Lyons NF, Wilson PC, Connolly MC, Crane WA
Jazyk: angličtina
Zdroj: British journal of obstetrics and gynaecology [Br J Obstet Gynaecol] 1980 Feb; Vol. 87 (2), pp. 169-73.
DOI: 10.1111/j.1471-0528.1980.tb04512.x
Abstrakt: A 26-year-old African female presented with primary amenorrhoea and genital abnormalities. She had the physical stigmata of Turner's syndrome and a 45, X karyotype. Severe masculinization of the external genitalia, apparently present from birth, was present and a laparotomy revealed a hilus-cell tumour of the right streak gonad. Clitoridectomy and vaginoplasty were performed but subsequent oestrogen therapy failed to produce breast development.
Databáze: MEDLINE