| Autor: |
Solbakken JE, Palmork KH, Neppelberg T, Scheline RR |
| Jazyk: |
angličtina |
| Zdroj: |
Acta pharmacologica et toxicologica [Acta Pharmacol Toxicol (Copenh)] 1980 Feb; Vol. 46 (2), pp. 127-32. |
| DOI: |
10.1111/j.1600-0773.1980.tb02431.x |
| Abstrakt: |
Metabolites present in the urine and bile of coalfish (Pollachius virens) 48 hrs after the intragastric administration of phenanthrene (75 mg/kg) were studied. Using gas chromatographic-mass spectrometric methods small amounts of unchanged compound, all five of the possible monohydroxy derivatives and the 1,2- and 9,10-dihydrodiols of phenanthrene were identified inthese samples. The major metabolite detected was phenanthrene-1,2-dihydrodiol which was excreted mainly as glucuronide and/or sulfate conjugates. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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