Heparin cofactor activity during and after extracorporeal circulation with bubble and membrane oxygenators.

Autor: Weiss M, Blass J, Leau A, Verriest C
Jazyk: angličtina
Zdroj: Biomedicine / [publiee pour l'A.A.I.C.I.G.] [Biomedicine] 1977 Oct; Vol. 27 (7), pp. 248-9.
Abstrakt: Heparin cofactor activity as measured by an amidolytic method has been investigated in 48 patients undergoing cardiac surgery with extra-corporeal circulation (E.C.C.). Heparin cofactor activity is reduced soon after the start of E.C.C., due to hemodilution but it returns towards initial levels at the completion of the procedure and 3 hours later. Thus heparin cofactor does not seem to play a role in the heparin rebound phenomenon. In our patients bubble oxygenators did not modify heparin cofactor activity more than did membrane oxygenators.
Databáze: MEDLINE