Assignment of the glyoxalase II gene (HAGH) to human chromosome 16.

Autor: Honey NK, Shows TB
Jazyk: angličtina
Zdroj: Human genetics [Hum Genet] 1981; Vol. 58 (4), pp. 358-61.
DOI: 10.1007/BF00282815
Abstrakt: The human and rodent forms of glyoxalase II (Hydroxyacylglutathione hydrolase, HAGH) can readily be separated by starch gel electrophoretic procedures. Fifty-one human-rodent somatic cell hybrid clones were examined for their human HAGH and for human enzyme markers whose genes are encoded on each autosome and the X chromosome. Sixteen clones were also examined for their human karyotypes. Human glyoxalase II segregated only with chromosome 16, demonstrating that the gene is located on this chromosome.
Databáze: MEDLINE