| Autor: |
Kachalov IuP, Nozdrachev AD, Pogorelov AG |
| Jazyk: |
ruština |
| Zdroj: |
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova [Fiziol Zh SSSR Im I M Sechenova] 1978 Nov; Vol. 64 (11), pp. 1530-9. |
| Abstrakt: |
In the isolated in vitro segments of cat small intestine the sensitivity of myenteric neurons was studied by means of application of acetylcholine, nicotine, lobeline. The action of these drugs depended on their concentration: 10(-10)--10(-6)g/ml usually increased while larger concentrations (10(-5)g/ml) decreased the spontaneous activity. The preliminary application of d--tubocurarine (10(-6)g/ml), hexamethonium (10(-7)g/ml), and atropine (10(-6)g/ml) prevented the excitatory effects or suppressed neuronal discharges. The alteration of spontaneous activity seems to depend on the postsynaptic action of cholinergic drugs in M- and N-cholinoreceptors. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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