[Fatty acid composition of lipid fractions of arterial walls, blood plasma and adipose tissue after sudden death from coronary disease].

Autor: Aptekar' SG, Vikhert AM
Jazyk: ruština
Zdroj: Voprosy meditsinskoi khimii [Vopr Med Khim] 1981; Vol. 27 (4), pp. 514-8.
Abstrakt: In patients with atherosclerosis of aorta and heart coronary arteries, diagnosed at autopsy, fatty acid composition was studied and analyzed in main lipid fractions of blood plasma, in unaltered intima of aorta and in the vascular tissue under conditions of various atherosclerotic impairments; simultaneously, fatty acid composition of triglycerides was studied in fatty tissues. The data obtained suggest that in arterial wall cholesterol might be esterified by linoleic acid liberated from lecithin. Analysis of fatty acid composition from blood plasma and arterial wall of the same patient demonstrated that blood plasma as well metabolic reactions, occurring immediately in arterial wall, influenced the composition of fatty acids in lipid fractions of the normal and atherosclerotically impaired arterial walls.
Databáze: MEDLINE