[Role of the spleen in regulating thrombocytopoiesis].

Autor: Abesadze AI, Bogvelishvili MV, Kvernadze MG, Iosava GG
Jazyk: ruština
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1978 Dec; Vol. 86 (12), pp. 718-20.
Abstrakt: It was shown in experiments on dogs that splenectomy resulted in thrombocytosis, as well as in a decrease of the adhesive-aggregation capacity of platelets and their average life span. Daily thrombocytopoiesis was increased, and a sharp shift in megakariocytogram toward mature forms was noted. Megakaryocytes count in the bone marrow decreased. It is suggested that a factor controlling megakaryocytes cells precursors differentiation was produced in the spleen.
Databáze: MEDLINE