| Autor: |
Nelson KF, North DS, Payne GR, Anderson AD, Poulson RE, Farrier DS |
| Jazyk: |
angličtina |
| Zdroj: |
Archives of environmental contamination and toxicology [Arch Environ Contam Toxicol] 1978; Vol. 7 (3), pp. 273-81. |
| DOI: |
10.1007/BF02332055 |
| Abstrakt: |
The effects of in situ-produced oil shale retort water on the metabolism of various substrates was studied both in vivo and in vitro. The induction observed in rats was classified as Type I due to an increase in metabolism of hexobarbital and ethylmorphine without subsequent increases in zoxazolamine metabolism. The maximal absorption of the cytochrome-P450-CO complex was observed to be 450 millimicron, also consistent with Type I inducers. Cytochrome P-450 levels were also significantly increased over controls. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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