| Autor: |
Mich TF, Huang GG, Woo PW, Sanchez JP, Heifetz CL, Schweiss D, Krolls U, Hutt MP, Chlbertson TP, Haskell TH |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of antibiotics [J Antibiot (Tokyo)] 1980 Nov; Vol. 33 (11), pp. 1352-6. |
| DOI: |
10.7164/antibiotics.33.1352 |
| Abstrakt: |
A new broad spectrum semisynthetic cephalosporin (CN-92,982) was prepared from the condensation of an acetylaminoacylaminophenyl pyridone with trans-7-[(D-2-phenylglycyl) amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-delta 3-cephem-4-carboxylic acid. The new cephalosporin displayed an in vitro antibacterial spectrum similar to other cephaloglycine types such as cefoperazone and SM-1652. The compound produced a high and prolonged blood level following a single intramuscular dose in a dog. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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