Autor: |
Naoum PC, Teixeira UA, de Abreu Machado PE, Michelin OC |
Jazyk: |
angličtina |
Zdroj: |
Revista brasileira de pesquisas medicas e biologicas [Rev Bras Pesqui Med Biol] 1978 Oct; Vol. 11 (4-5), pp. 241-4. |
Abstrakt: |
Human oxyhaemoglobin A and A2 from normal individuals and oxyhaemoglobin S from patients with sickle cell anaemia and sickle cell trait were studied using Isopropanol/buffer method at 37 degrees C and 40 degrees C. Hb S was less stable than Hb A, whereas Hb A2 was considerably more stable than either. Denaturation of Hb S was dependent on temperature and its concentration. Between the patients with sickle cell trait it was not possible to verify the influence of the concentration probably due to the small range used (from 38% to 44%). |
Databáze: |
MEDLINE |
Externí odkaz: |
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