| Autor: |
Cassimos C, Kanakoudi-Tsakalidis F, Spyroglou K, Ladianos M, Tzaphi R |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical & laboratory immunology [J Clin Lab Immunol] 1980 Mar; Vol. 3 (2), pp. 111-3. |
| Abstrakt: |
The skin reactivity to 2, 4 dinitrochlorobenzene (DNCB) was evaluated in 94 healthy term neonates, aged 1-30 days and in 190 infants aged 2-9 months. For contact sensitization to DNCB an initial dose of 1 mg DNCB and a challenge one of 0.1 mg were used. Sensitization was induced in 6.7% of neonates in the first 15 days of life. This proportion rose to 25.7% by the end of the first month, to 63% in the third month and to 91% in the ninth month. It is concluded that DNCB test is a safe and simple screening test for evaluating cell-mediated immunity in the first months of life. It appears to have some advantages over the skin tests using specific antigens, as a positive result with DNCB can be obtained at an earlier age. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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