Low plasma cortisol and hematologic abnormalities associated with essential fatty acid deficiency in man.

Autor: Bistrian BR, Bothe A Jr, Blackburn GL, DeFriez AI
Jazyk: angličtina
Zdroj: JPEN. Journal of parenteral and enteral nutrition [JPEN J Parenter Enteral Nutr] 1981 Mar-Apr; Vol. 5 (2), pp. 141-4.
DOI: 10.1177/0148607181005002141
Abstrakt: A case of probable adrenal insufficiency (glucocorticoid only) with hematologic changes including eosinophilia, neutropenia, and red blood cell abnormalities developed in the course of prolonged, fat-free feeding. The coincident development of essential fatty acid deficiency was conformed by serum fatty acid profiles indicating the presence of abnormal amounts of eicosatrienoic acid, and a triene/tetraene ratio greater than 0.4; all these findings responded to fat repletion. The association of glucocorticoid deficiency, neutropenia, and eosinophilia with essential fatty acid deficiency has not been previously reported in humans.
Databáze: MEDLINE