[Effect of gidifen on behavior and hemodynamic signs of an emotionally stressful reaction].

Autor: Val'dman AV, Kozlovskaia MM, Zaikonnikova IV, Bravkov MF, Rzhevskaia GF
Jazyk: ruština
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1980 Mar; Vol. 89 (3), pp. 310-2.
Abstrakt: Gidifen (diphenylphosphinylacetic acid hydrazide) is an original Soviet tranquilizer. In doses of 120--150 mg/kg it restores central baroreflex regulation of the arterial pressure supressed during acute emotional-stress reaction in cats (confrontation with a dog). The drug has an antihypertensive action and reduces tachycardia caused by the emotional stress. It has a selective antiphobic and antiaggressive action and does not produce ataxia. Quantitative evaluation of behavior was performed during group interaction of animals according to the five-point system.
Databáze: MEDLINE