The postnatal acquisition of factors which affect the influenza haemagglutination-inhibition test.

Autor: Grint PC, Argent S, Heath RB
Jazyk: angličtina
Zdroj: The Journal of hygiene [J Hyg (Lond)] 1982 Oct; Vol. 89 (2), pp. 329-34.
DOI: 10.1017/s0022172400070868
Abstrakt: Levels of maternally transferred antibodies against the surface antigen of the A/Texas/1/77 strain of influenza virus showed the expected decline during infancy when measured by complement fixation (CF). However, this decline was not observed when these antibodies were measured by haemagglutination-inhibition (HI). It has been postulated that this discrepancy is due to the acquisition, in the early days of life, of non-specific serum factors which increase the HI activity of sera. The levels of these factors were determined indirectly by calculating HI:CF ratios and it was shown that the factors are rapidly acquired by children between the fifth and twentieth week of life.
Databáze: MEDLINE