[Effect of the water-soluble antioxidant hydroxypyridine-6 on the intensity of lipid peroxidation in eye tissues in experimental ophthalmic herpes].

Autor: Kasavina BS, Maĭchuk IuF, Dalgat LD, Romashchenko AD
Jazyk: ruština
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1982 Jul; Vol. 94 (7), pp. 27-8.
Abstrakt: Lipid peroxidation (LPO) in eye tissues of rabbits with experimental herpetic keratitis was evaluated from the malonic dialdehyde content and chemiluminescence intensity. It appeared that during the critical phase LPO sharply increased in all the tissues under study and in anterior chamber humor. After administration of the synthetic water-soluble antioxidant, hydroxypyridine-6 the subconjunctival content of malonic dialdehyde and chemiluminescence intensity approached normal values accompanied by positive therapeutic effect.
Databáze: MEDLINE