| Autor: |
Pivovarov IuI, Kryzhanovskiĭ GN |
| Jazyk: |
ruština |
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1982 Jun; Vol. 93 (6), pp. 27-30. |
| Abstrakt: |
It was shown in experiments on random-bred rats that changes in the heart reactivity caused by adrenaline, rausedyl, potassium chloride and strophanthine facilitate the occurrence of cardiac rhythm abnormalities during the creation of the generator of pathologically enhanced excitation (GPEE) in the anterior amygdaline nucleus. The moments of rhythm abnormalities correlate with the occurrence of GPEE epileptic activity. Meanwhile the pattern of cardiac rhythm abnormalities is largely determined by the specificity of action of the pharmacological substances indicated. Analogous effects of cardiac rhythm abnormality facilitation during GPEE creation in the nucleus were obtained in myocardial ischemia caused by the occlusion of the anterior or posterior left coronary artery. At the same time the differences were recorded in the pattern of cardiac rhythm abnormalities depending on the area of ischemia. The data obtained are discussed in the light of concepts of regulation diseases, particularly of the correlation between the role of determinant structures and reactivity disorders in the target organs. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
