Evidence for beta-adrenergic activation of Na+-dependent efflux of Ca2+ from isolated liver mitochondria.
| Autor: | Goldstone TP, Crompton M |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | The Biochemical journal [Biochem J] 1982 Apr 15; Vol. 204 (1), pp. 369-71. |
| DOI: | 10.1042/bj2040369 |
| Abstrakt: | The existence of a Na(+)-dependent mechanism for Ca(2+) efflux from isolated rat liver mitochondria was confirmed. The activity of this system is decreased by 60% in mitochondria isolated from perfused livers. The Na(+)-dependent activity is fully restored by infusion of either 1mum-adrenaline or 1mum-isoprenaline, but the alpha-adrenergic agonist phenylephrine is ineffective. |
| Databáze: | MEDLINE |
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