| Autor: |
Gedevanishvili MD, Tsutsunava LE, Malazoniia NA |
| Jazyk: |
ruština |
| Zdroj: |
Tsitologiia [Tsitologiia] 1982 Feb; Vol. 24 (2), pp. 224-6. |
| Abstrakt: |
The influence of serotonin on the adhesion and growth processes in primary cultures of murine and human embryo fibroblasts and L-cells was studied separately. At the moment of seeding, serotonin shortened the time of adhesion of glass surface of these from approximately 4 to 1 or 2 hours and stimulated incorporation of tritiated thymidine and cell multiplication when introduced in 2- or 6-hour cultures. Adhesion- and growth- stimulatory activities were blocked by serotonin antagonists - cyproheptadine and tipindole, demonstrating that the specific binding of bioamine with cell receptors is essential in both the cases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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