| Autor: |
Kostenko MA, Tretjak NN, Musienko VS |
| Jazyk: |
angličtina |
| Zdroj: |
Brain research [Brain Res] 1982 Mar 18; Vol. 236 (1), pp. 183-92. |
| DOI: |
10.1016/0006-8993(82)90044-0 |
| Abstrakt: |
The number of viable neurones calculated as soon as adult mollusc ganglia tissue was digested and over different periods of cultivation, show that elevated K+ prevents degradation of intercellular contacts, preserves neurones against lysis, prolongs the time course of neurone survival in culture and inhibits neurite formation. K+ depolarizing effect is maintained throughout the whole course of cultivation; when elevated K+ is substituted by normal K+ the resting potential of neurones recovers. The effect of elevated K+ on neurone survival and the capability for neurite formation is not due to membrane depolarization, but seems to be related to an influence on intracellular ionic homeostasis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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