[State of protein and mineral metabolism following thyrocalcitonin administration during experimental osteogenesis].

Autor: Khomullo GV, Travkina VM, Ryzhova TI, Kokoreva GA
Jazyk: ruština
Zdroj: Voprosy meditsinskoi khimii [Vopr Med Khim] 1978 Sep-Oct; Vol. 24 (5), pp. 613-7.
Abstrakt: Prolonged administration of thyrocalcitonine (TC) into rats (at a dose 5 un per animal) led to some alterations in protein and mineral metabolism: decrease in content of calcium and phosphorus in blood, activation of alkaline phosphatase in blood, decrease in excretion of hydroxyproline, increase in excretion of aminonitrogen with urine. Distinct correlation was observed between the metabolic activity and definite steps in reparative osteogenesis. Exogenous TC activated the cellular structures, which participated in the regenerative processes, promoted the rapid turnover of bone generation and decreased the periods of tracture healing.
Databáze: MEDLINE