| Autor: |
Jones RN, Wilson HW, Novick WJ Jr, Barry AL, Thornsberry C |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical microbiology [J Clin Microbiol] 1982 May; Vol. 15 (5), pp. 954-8. |
| DOI: |
10.1128/jcm.15.5.954-958.1982 |
| Abstrakt: |
CENTA is a newly synthesized, beta-lactamase-labile, chromogenic cephalosporin reagent which changes color from light yellow (lambda maximum ca. 340 nm) to chrome yellow (lambda maximum ca. 405 nm) concomitant with hydrolysis of the beta-lactam ring. This compound offers promise as a diagnostic reagent comparable to other chromogens (PADAC and nitrocefin) for the early detection of beta-lactamase-producing clinical isolates, while retaining some antimicrobial effect against Escherichia coli, Klebsiella spp., Proteus mirabilis, Staphylococcus aureus, and non-enterococcal Streptococcus spp. CENTA is relatively unaffected by commonly used microbiological media and human serum. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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