Four-year follow-up on the Albany experience with intrapleural BCG in lung cancer.

Autor: McKneally MF, Maver C, Lininger L, Kausel HW, McIlduff JB, Older TM, Foster ED, Alley RD
Jazyk: angličtina
Zdroj: The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 1981 Apr; Vol. 81 (4), pp. 485-92.
Abstrakt: One hundred sixty-nine patients were entered into randomized controlled studies of intrapleural bacille Calmette Guérin (BCG) immunotherapy after surgical resection of lung cancer. Long-term follow-up of our initial series of BCG-treated patients with Stage I disease continues to indicate that this treatment was superior to that given to control patients. The recurrence rate in the control population was high, 62% at 3 years. The recurrence rate was 33% at 3 years in the BCG-treated group. A negative preoperative tuberculin test and squamous cell histologic type were favorable prognostic factors for BCG-treated patients. The survival of patients with more advanced disease was not improved by BCG immunotherapy.
Databáze: MEDLINE