Autor: |
Sveshnikova NA, Mal'tseva NN, Khabakhpasheva NA |
Jazyk: |
ruština |
Zdroj: |
Voprosy virusologii [Vopr Virusol] 1980 Sep-Oct (5), pp. 631-5. |
Abstrakt: |
The successful application of the immunoperoxidase method of (IP) with light microscopy for rapid detection of certain togaviruses and orthopoxviruses and antibodies to them is described. A comparative evaluation of the IP and immunofluorescent (IF) method for these purposes was performed. The results indicate practically similar sensitivity and specificity of both methods. The detection of viral antigen directly depended upon the infective dose and time of examinations (within 4--12 hours postinoculation). In evaluating the IP method, however, the account should be taken of the fact that it does not require expensive equipment and therefore may be used in any practical laboratory or even under field conditions. Rapid detection of both viral antigens and antiviral antibody by this method opens approaches for its wide application in the future. |
Databáze: |
MEDLINE |
Externí odkaz: |
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