| Autor: |
Man'ko VM, Saiadian KhS, Khalatian NA |
| Jazyk: |
ruština |
| Zdroj: |
Tsitologiia [Tsitologiia] 1981 Mar; Vol. 23 (3), pp. 333-9. |
| Abstrakt: |
Bone marrow stem cells of the parent genotype (CBA) produce mainly erythroid colonies in the spleen of lethally irradiated recipients (CBA-C57Bl)F1. T d-lymphocytes change this differentiation pattern from the mainly erythroid to the mainly myeloid pathway. The irradiation with 100 R does not abolish this effect. The lymphocytes irradiated in vitro with 200 R or more, and incubated with Mitomycin C or Cycloheximide lost the ability to change the differentiation pattern of the transplanted cells. T d-lymphocytes are radiosensitive cells that need DNA and protein synthesis for realizing their function. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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