| Autor: |
Skliar MI, Fernandez MC, Faienza H, Orsatti MB, Puche RC, Boland RL, Skliar MI |
| Jazyk: |
angličtina |
| Zdroj: |
Pflugers Archiv : European journal of physiology [Pflugers Arch] 1980 Dec; Vol. 389 (1), pp. 81-3. |
| DOI: |
10.1007/BF00587932 |
| Abstrakt: |
The erythrocytes of rats treated with 1, 25-dihydroxycholecalciferol or 1, 25-dihydroxycholecalciferol glycoside showed decreased levels of 2, 3-diphosphoglycerate. The same result has been obtained in vitro, indicating a direct effect of the sterol on the red cell. The glycoside is less active than the free sterol in vivo and more active in vitro. The decreased levels of diphosphoglycerate induced tissue hypoxia as shown by a higher plasma lactate/pyruvate ratio and a three fold increase in plasma erythropoietin concentration. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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