| Autor: |
Ransohoff DF, Gracie WA, Wolfenson LB, Neuhauser D |
| Jazyk: |
angličtina |
| Zdroj: |
Annals of internal medicine [Ann Intern Med] 1983 Aug; Vol. 99 (2), pp. 199-204. |
| DOI: |
10.7326/0003-4819-99-2-199 |
| Abstrakt: |
Decision analysis was done to compare the consequences of prophylactic cholecystectomy with expectant management for silent gallstone disease. Probability values were derived from a study of the natural history of silent gallstone disease, published cholecystectomy mortality rates, and life tables. The two strategies were compared by calculating cumulative numbers of person-years lost for hypothetical cohorts of men and women. Prophylactic cholecystectomy slightly decreases survival. A 30-year-old man choosing prophylactic cholecystectomy instead of expectant management would lose, on average, 4 days of life; a 50-year-old man would lose 18 days. Consideration of monetary costs and discounting further disfavors prophylactic cholecystectomy. Sensitivity analysis shows that differences between the two strategies remain small over a broad range of probability values, both for men and women. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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