| Autor: |
Luderer AA, Borrelli NF, Panzarino JN, Mansfield GR, Hess DM, Brown JL, Barnett EH, Hahn EW |
| Jazyk: |
angličtina |
| Zdroj: |
Radiation research [Radiat Res] 1983 Apr; Vol. 94 (1), pp. 190-8. |
| Abstrakt: |
Hyperthermia has been found to be a useful modality for cancer therapy. In this report, a biocompatible, ferrimagnetic glass-ceramic capable of inducing localized hyperthermia by hysteresis heating upon exposure to an alternating magnetic field is presented. When the glass-ceramic was placed in the region of a subcutaneously transplanted, weakly antigenic breast carcinoma and subjected to the magnetic field, sufficient temperature rise was obtained to cause significant (approximately 50%) tumor regrowth delay and a 12% permanent control. The data demonstrate that glass-ceramic-mediated hysteresis heating may be a useful therapeutic approach in the treatment of cancer which offers the advantage of producing a highly localized and predictable tumor volume hyperthermia. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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