Formaldehyde and hexamethylenetetramine in Styles' cell transformation assay.

Autor: Plesner BH, Hansen K
Jazyk: angličtina
Zdroj: Carcinogenesis [Carcinogenesis] 1983; Vol. 4 (4), pp. 457-9.
DOI: 10.1093/carcin/4.4.457
Abstrakt: A dose-dependent increase in the transformation rate in Styles' cell transformation assay using BHK-21/cl.13 cells was observed after exposure to formaldehyde and hexamethylenetetramine. The toxic and transforming effect was equal after exposure to 20 micrograms/ml of formaldehyde or 1000 micrograms/ml of hexamethylenetetramine which is slowly hydrolysed in aqueous solution to form ammonia and formaldehyde.
Databáze: MEDLINE