| Autor: |
Greene JW, Craft L, Ghishan F |
| Jazyk: |
angličtina |
| Zdroj: |
American journal of diseases of children (1960) [Am J Dis Child] 1983 Apr; Vol. 137 (4), pp. 386-7. |
| DOI: |
10.1001/archpedi.1983.02140300064018 |
| Abstrakt: |
Acetaminophen is widely used in children of all ages, and overdosage from this medication is common. Although severe hepatotoxicity from over-dosage occurs in adults, acetaminophen seems to have a wide margin of safety in younger children. This has been ascribed to altered pharmacokinetics in this age group. We report two cases in which severe acetaminophen-induced hepatoxocity occurred in two infants. Neither infant reportedly received potentially toxic dosages, by history, but toxic drug levels were present in both. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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