| Autor: |
Vasmant D, Bensman A, Baudon JJ, Rathery S, Lasfargues G |
| Jazyk: |
francouzština |
| Zdroj: |
Annales de medecine interne [Ann Med Interne (Paris)] 1982; Vol. 133 (4), pp. 276-80. |
| Abstrakt: |
A 2-year-old boy with familial extramembranous glomerulonephritis was unfortunately treated with corticosteroids (1 to 0.5 mg/kg/day) and Chlorambucil (cumulative dose: 2.5 g) over a period of 7 years. Three years later, after recovery from the renal affection, he developed fatty diarrhoea from exocrine pancreatic deficiency, followed 5 years later by the onset of diabetes with hypochlorhydric gastritis. The diagnosis of non-calcifying chronic pancreatitis was suggested by scintigraphic and ultrasonographic investigations and confirmed by the marked increase in lactoferrin levels and the lactoferrin/lipase ratio (greater 0.1 p. cent) in pancreatic juice. The etiology was more likely to be direct toxicity of corticoids and/or immunosuppressors on the pancreas than an immunologically-mediated disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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