| Autor: |
Martinez-A C, Coutinho A, Bernabé RR |
| Jazyk: |
angličtina |
| Zdroj: |
Scandinavian journal of immunology [Scand J Immunol] 1981; Vol. 13 (1), pp. 41-6. |
| DOI: |
10.1111/j.1365-3083.1981.tb00109.x |
| Abstrakt: |
Helper T cells raised in CBA mice and enriched in vitro with specificity for trinitrophenylmodified syngeneic spleen cells can activate hapten-modified B cells bearing Ik. These helper cells fail to activate B cells expressing any of six independent I-region haplotypes, indicating lack of cross-reactivity between hapten-self and allogeneic I-region products. Furthermore, hapten-derivatized allogeneic B cells are also not activated, demonstrating that the elements restricting T-cell function are poorly, if at all, cross-reactive. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Plný text