Autor: |
Lazarus JH, John R, Bennie EH, Chalmers RJ, Crockett G |
Jazyk: |
angličtina |
Zdroj: |
Psychological medicine [Psychol Med] 1981 Feb; Vol. 11 (1), pp. 85-92. |
DOI: |
10.1017/s0033291700053307 |
Abstrakt: |
Seventy-three patients who had been continuously receiving lithium carbonate for 6 months or more had their thyroid function evaluated clinically and biochemically. Goitre was found in 37%, exophthalmos in 23%, positive thyroid auto-antibodies in 24% and abnormal TRH tests in 49%. It would appear that thyroid failure due to lithium is usually dependent on antibody mediated damage. It is unlikely that lithium has a direct effect on the hypothalamic-pituitary axis. |
Databáze: |
MEDLINE |
Externí odkaz: |
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