| Autor: |
Brusick DJ, Jagannath DR, Matheson D |
| Jazyk: |
angličtina |
| Zdroj: |
Mutation research [Mutat Res] 1982 Dec; Vol. 102 (4), pp. 361-72. |
| DOI: |
10.1016/0165-1218(82)90099-4 |
| Abstrakt: |
2-(2',4'-Diaminophenoxy)-ethanol, a hair-dye ingredient was evaluated for genetic activity in vitro using urine collected from mice in an Ames test and in vivo using the mouse dominant-lethal assay and the mouse spot test for somatic mutation detection. All 3 studies were conducted using dermal application of the dye material to shaved skin. The applied dose levels ranged from 15 to 1500 mg/kg body weight. The results of these 3 studies were considered to be negative although urine analysis and spot-test data showed non-significant dose-related increases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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