| Autor: |
Grose EC, Richards JH, Illing JW, Miller FJ, Davies DW, Graham JA, Gardner DE |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of toxicology and environmental health [J Toxicol Environ Health] 1982 Sep; Vol. 10 (3), pp. 351-62. |
| DOI: |
10.1080/15287398209530258 |
| Abstrakt: |
The effects of simultaneous exposure to ozone (O3) and sulfuric acid [H2SO4, 0.23 microns volume median diameter (VMD)] and a single exposure to ultrafine (less than 0.1 micron VMD) H2SO4 under various conditions were studied using the infectivity/mortality and the ciliary beating frequency model systems. A 3-h exposure to a combined aerosol of 196 micrograms O3/m3 and 483 or 241 micrograms H2SO4/m3 significantly increased the susceptibility of mice to a laboratory-induced respiratory infection. However, exposure to 543 micrograms ultrafine H2SO4/m3 for 2 h or 365 micrograms/m3 2 h/d for 5 d did not significantly affect this parameter. Upper airway response, as measured by changes in hamster tracheal ciliary beating frequency, was not affected by either a 3-h combined exposure to 196 micrograms O3/m3 and 847 micrograms H2SO4/m3 or a 2-h exposure to 458 micrograms ultrafine H2SO4/m3. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
