| Autor: |
Pouillart P, Palangie T, Jouve M, Langlois A, Garcia-Giralt E, Regensberg C, Blic V, Huguenin P, Morin P, Gautier H, Baron A, Dat-Xuong |
| Jazyk: |
francouzština |
| Zdroj: |
La Nouvelle presse medicale [Nouv Presse Med] 1978 Jun 24; Vol. 7 (25), pp. 2235-8. |
| Abstrakt: |
Thirty nine patients with non resectable colonic carcinoma entered into a phase II combination chemotherapy trial. The patients were treated with a sequential cyclic combination of 3 drugs: VM 26 (60 mg/m2), methyl-C.C.N.U. (120 mg/m2) and 5 fluoro-uracile. Seventeen patients out of 39 (43.6%) are considered as good responders. The median survival time of the overall of this group is 12.6 months; it is of 15,6 months for good responders and of 7 months for non responders. The simultaneous application of B.C.G. do not change neither the level of responses nor the median of survival time. The good tolerance of this protocol let us to propose this combination as an adjuvant treatment for patients surgically treated for a Dukes'C colonic cancer. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
