| Autor: |
Grossman CJ, Sholiton LJ, Helmsworth JA |
| Jazyk: |
angličtina |
| Zdroj: |
Steroids [Steroids] 1983 Jul; Vol. 42 (1), pp. 11-22. |
| DOI: |
10.1016/s0039-128x(83)90048-x |
| Abstrakt: |
Dihydrotestosterone receptor was prepared from both the cytoplasm and nucleus of human thymic tissue. Human cytoplasmic and nuclear dihydrotestosterone receptor possessed a KA greater than 1.0 and by competition assay was highly specific for dihydrotestosterone. Human thymic cytoplasmic dihydrotestosterone receptor prepared in standard buffer sedimented on 5-20% sucrose gradients in the 4s region but human thymic cytoplasmic dihydrotestosterone receptor prepared in buffer containing sodium molybdate (10 mM) sedimented in the 7s region on 5-20% sucrose gradients. It is concluded that the human thymic dihydrotestosterone receptor is similar to classic androgen receptor. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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