| Autor: |
Terebelo HR, Taylor HG, Brown A, Martin N, Stutz FH, Blom J, Geier L |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 1983 Sep; Vol. 1 (9), pp. 566-71. |
| DOI: |
10.1200/JCO.1983.1.9.566 |
| Abstrakt: |
The complete response (CR) rate of disseminated germ-cell tumors with current aggressive chemotherapy and surgical resection of localized residual disease is between 70%-80%. Most patients who relapse do so within the first year of therapy. We have observed seven patients with germ-cell tumors treated with a variety of modalities who relapsed after more than two years in CR (45-87 months). Five patients are alive after salvage therapy with follow-up too short to assess the durability of second remission. There were no features distinguishing late relapse patients from all patients treated with chemotherapy for germ-cell tumors. Follow-up in patients treated for germ-cell tumors with chemotherapy should be extended to five years before curability can be established. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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