In vitro effect of certain compounds on the lysosomal release of polymorphonuclear leukocytes.
| Autor: | Chari SN, Nath N, Rathi AB |
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| Jazyk: | angličtina |
| Zdroj: | Indian journal of physiology and pharmacology [Indian J Physiol Pharmacol] 1983 Jul-Sep; Vol. 27 (3), pp. 227-33. |
| Abstrakt: | From studies on the release of acid phosphatase and B-glucuronidase, it was observed that quercetin, a vitamin P like compound and ascorbic acid stablise while dehydroascorbate, acetoacetate and B-hydroxybutyrate labilise the leukocytic lysosomes in vitro. These effects were compared with chloroquine and progesterone, known stabiliser and destabiliser, respectively. The possible mode of lysosomal labilisation by ketone bodies and dehydroascorbate has been suggested. |
| Databáze: | MEDLINE |
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