[Synthesis and antibacterial activity of perchlorylchloramphenicol].
| Autor: | Ziebell G, Gross H, Bradler G |
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| Jazyk: | němčina |
| Zdroj: | Die Pharmazie [Pharmazie] 1983 Sep; Vol. 38 (9), pp. 587-9. |
| Abstrakt: | Starting from p-perchloryl acetophenone we have synthesized the perchloryl analogue of chloramphenicol. The new compound is the first chloramphenicol analogue possessing a higher antimicrobial activity as chloramphenicol itself. It showed an about twofold activity against 18 different microbes in the hole plate diffusion test, compared with the parent compound. |
| Databáze: | MEDLINE |
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