| Autor: |
Angier RB, Citarella RV, Damiani M, Fabio PF, Fields TL, Kang SM, Lin Y, Lindh HF, Murdock KC, Petty SR, et. al. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of medicinal chemistry [J Med Chem] 1983 Dec; Vol. 26 (12), pp. 1710-5. |
| DOI: |
10.1021/jm00366a010 |
| Abstrakt: |
A series of 3,6-bis(aminoalkoxy)acridines (2) was prepared and shown to have a protective antiviral effect against an interferon-sensitive virus (Columbia SK) and to partially restore an antibody response to a T-cell-dependent antigen in leukemic immunosuppressed mice. The presence of circulating interferon and the stimulation of natural killer cell activity in mice was observed for 21. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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