Autor: |
Ivanov LL, Lukoshiavichius LIu, Kovalenko MI, Bagdonaĭte OD, Lekis AV |
Jazyk: |
ruština |
Zdroj: |
Ukrainskii biokhimicheskii zhurnal (1978) [Ukr Biokhim Zh (1978)] 1983 Jul-Aug; Vol. 55 (4), pp. 368-71. |
Abstrakt: |
The composition of high-molecular complexes of aminoacyl-tRNA-synthetases (ARSase) from the rabbit liver was studied on the first day after reproduction of the experimental myocardium infarction. The studies revealed an increase in the glutamyl-, leucyl-, lysyl- and a decrease in the glycyl- and seryl-tRNA-synthetase activities and redistribution of the last two enzymes from the composition of the complexes into a lower-molecular fraction of postribosomal supernatant fluid. Under the experimental myocardium infarction the complexes reveal a significant decrease in the content of phospholipids and variations in the electrophoretic mobility of protein fractions. An assumption is advanced that a disturbed protein biosynthesis in the liver resulted from the experimental myocardium infarction causes changes in the structural organization of the ARSase complexes. |
Databáze: |
MEDLINE |
Externí odkaz: |
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